Allied Academies welcomes all the attendees, speakers, sponsor’s and other research expertise from all over the world to the "12th International Conference on Cancer Stem Cells and Oncology Research” (Cancer Stem Cells-2019) which is going to be held during March 15-17, 2019 in Rome, Italy. We are very much honored to invite you all to exchange and share your views and experience on Caner Stem Cells: Targeting Cancer Stem Cells to Transform Cancer Therapies.
Allied Academies Organizes Cancer Stem Cells 2019 conference along with 300+ Conferences across USA, Europe & Asia every year with support from 1000 more scientific societies and Publishes 400+ Open access journals which contains over 30000 eminent personalities as editorial board members.
We invite you to join us at the Cancer Stem Cells-2018, where you will be sure to have a meaningful experience with scholars from around the world. All members of the Cancer Stem Cells-2018 organizing committee look forward to meeting you in Dublin, Ireland.
Established in the year 1997, Allied Academies Publication
is an amalgamation of several esteemed academic and scientific
associations known for promoting scientific temperament.
Allied Academies invites all the participants from all over the world to attend "12th International Conference on Cancer Stem Cells and Oncology Research”, on March 15-17, 2019 in Rome, Italy which includes prompt keynote presentations, oral talks, poster presentations and exhibitions.
Cancer stem cells (CSCs) are cancer cells (found within tumors or haematological cancers) that possess characteristics associated with normal stem cells, specifically the ability to give rise to all cell types found in a particular cancer sample. CSCs are therefore tumorigenic (tumour-forming), perhaps in contrast to other non-tumorigenic cancer cells. CSCs may generate tumors through the stem cell processes of self-renewal and differentiation into multiple cell types. Such cells are hypothesized to persist in tumors as a distinct population and cause relapse and metastasis by giving rise to new tumors. Therefore, development of specific therapies targeted at CSCs holds hope for improvement of survival and quality of life of cancer patients, especially for patients with metastatic disease.
Cancer Stem Cells 2019 is
a platform to fulfill the prevailing gaps in the transformation of this
science of hope, to serve promptly with solutions to all in the need.
Cancer Stem Cells 2018 will have an anticipated participation of 120+
delegates across the world to discuss the conference goal.
Allied Academies is one of the leading Open Access publishers and organizers of international scientific conferences and events every year across USA, Europe & Asia. Allied Academics has so far organized 3000+ Global Allied Academics Events with over 600+ Conferences, 1200+ Symposiums and 1200+ Workshops on Medical, Pharma, Engineering, Science, Technology and Business with 700+ peer-reviewed open access journals in basic science, health, and technology.
Cancer Stem Cells 2019 will encompass recent researches and findings in Cancer stem cells technologies, Cancer stem cells therapies and transplantation, current understanding of cell plasticity in cancer and other advancements in Cancer stem cells research and cell science. Cancer Stem Cells 2019 will be a great platform for research scientists and young researchers to share their current findings in this field of applied science. The major scientific sessions in Cancer Stem Cells 2019 will focus on the latest and exciting innovations in prominent areas of Cancer cell science and Cancer stem cells research.
Eminent personalities, Directors, CEO, President, Vice-president, Organizations, Associations Heads and Professors, Research scientists, Cancer Stem Cell laboratory heads, Post-docs, Students other affiliates related to the area of Cancer Stem cells research, regenerative medicine can be as Target Audience.
Sessions and Tracks
Allied Academies International
Conferences invites all the participants from all over the world to
attend "12th International Conference on Cancer Stem Cells and Oncology
Research" during March 15-17, 2019 in Rome, Italy which includes
prompt keynote presentations, oral talks, poster presentations and
Track: Cancer Stem Cells
Cancer stem cells are rare immortal cells within a tumour that can both self-renew by dividing and give rise to many cell types that constitute the tumour, and can therefore form tumors. Such cells have been found in various types of human tumors and might be attractive targets for cancer treatment.
Track: Cancer Stem Cells and Metastasis
Metastasis is the spread of a cancer or other disease from one organ or part of the body to another without being directly connected with it. When cancer cells break away from a tumour, they can travel to other areas of the body through the bloodstream or the lymph system. The lungs, liver, brain, and bones are the most common metastasis locations from solid tumors.
Track: Cancer Stem Cells and the Tumor Microenvironment
growing body of evidence indicates that the tumor microenvironment
contributes to tumor growth and viability, while significant advances
are being made in the understanding of cancer stem cells and tumor
initiating cells. The session will discuss on breaking developments on
novel tumor-killing strategies and preclinical and clinical projects
which are exploiting cancer stem cells, the inflammatory component of
tumors, and the tumor microenvironment for therapeutic intervention.
Track: Bio-markers of Cancer Stem Cells
Bio-marker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition.
Track: Cancer Genomics & Metabolomics
The main concept and idea of oncogenomics are to check a new group of oncogenes or tumour suppressor genes that may give new areas of research into cancer diagnosis, predicting clinical outcome of cancers and new targets for cancer therapies. Oncogenomics is a sub-field of genomics that characterizes cancer-associated or cancer-related genes. It focuses mainly on genomic, epigenomic and transcript alterations in cancer. The Gleevec, Herceptin and Avastin are the targeted cancer therapies which gave a new way for oncogenomics to elucidate new targets for cancer treatment. The metabolome represents the collection of all metabolites in a biological cell, tissue, organ or organism that are the end products of cellular processes and gives physiology of the given cell. One of the challenging aspects of systems biology and functional genomics is to integrate proteomic, transcriptomic, and metabolomic information which provide a better understanding of cellular biology.
Track: Immune systems in stem cells and cancer
Immuno-oncology is the new and emerging field of cancer research that works to understand the interaction of the immune system with cancers cells and finds ways for the harness of the patient’s immune system to treat or prevent cancer. It targets only the immune system, not the cancer cells. Recent advances in our understanding of antigen recognition, presentation and the molecules involved in T and B cell activation have provided new and excited immunotherapeutic strategies which can be used against the cancer cells. Some success in animal models has been observed and some molecules are now being in clinical trials.
Track: Clinical research and trials in stem cells and cancer
Cancer research focuses on stem cells present in malignant tumors. Researchers believe current cancer treatments sometimes fail because they don't destroy the cancer stem cells. Think of cancer as a weed: the stem cells are the root while the remaining majority of the cells are the part of the weed above ground. If you remove only the leaves but not the root, the weed will grow back. The same is true for cancer: if you do not kill the cancer stem cells, the cancer is likely to return.
Track: Stem Cell Transplantation for Cancer
Stem cell transplant (also called peripheral blood stem cell transplant) is a treatment to try to cure some types of cancer, such as leukemia, lymphoma and myeloma. You have very high doses of chemotherapy, sometimes with whole body radiotherapy. This has a good chance of killing the cancer cells but also kills the stem cells in the bone marrow. Stem cell transplant means that you can have higher doses of treatment. So there may be more chance of curing the cancer than with standard chemotherapy.
Track: Cancer Stem Cells Epigenetics
Epigenetic alterations including DNA methylation and histone modifications are the key factors in the differentiation of stem cells into different tissue subtypes. The generation of cancer stem cells (CSCs) in the process of carcinogenesis may also involve similar kind of epigenetic reprogramming where, in contrast, it leads to the loss of expression of genes specific to the differentiated state and regaining of stem cell-specific characteristics. The most important predicament with treatment of cancers includes the non-responsive quiescent CSC.Characterizing the epigenetic marks of CSCs and the associated signalling cascades might help in developing therapeutic strategies against chemo-resistant cancers.
Track: Breast Cancer Stem Cells
Breast cancer stem cells - the first to be identified in a solid tumour - were discovered in 2003 by scientists at the U-M Comprehensive Cancer Center. U-M scientists found that just a few cancer stem cells are responsible for the growth and spread of breast cancer. Unless the cancer stem cells are destroyed, the tumour is likely to come back and spread malignant cells to other parts of the body, a process called metastasis.
Track: Pancreatic Cancer Stem Cells
Pancreatic cancer stem cells have some similarities to cancer stem cells found in other types of cancer; however, there also appear to be some significant differences. This is why it is important to study the function of these cells in the specific cancer in which these cells arise to best understand their function. Regardless of the organ in which they are found, cancer stem cells appear to be responsible for the propagation of cancer and for its spread to other organs in the body.
Track: Embryonic Stem Cells
Embryonic stem cells (ES cells) are pluripotent stem cells derived from the inner cell mass of a blastocyst, an early-stage preimplantation embryo. Human embryos reach the blastocyst stage 4–5 days post fertilization, at which time they consist of 50–150 cells. Isolating the embryo blast or inner cell mass (ICM) results in destruction of the blastocyst, which raises ethical issues, including whether or not embryos at the pre-implantation stage should be considered to have the same moral or legal status as more developed human beings.
Track: Cancer Stem Cells in Brain Gliomas
Glioblastoma (GBM) is the most prevalent and malignant primary brain tumor and contains self-renewing, tumorigenic cancer stem cells (CSCs) that contribute to tumor initiation and therapeutic resistance. As normal stem and progenitor cells participate in tissue development and repair, these developmental programs re-emerge in CSCs to support the development and progressive growth of tumors.
Track: Hematopoietic and Chord blood stem cells
Cord blood stem cells are derived from the blood found in the vein of the umbilical cord. Cord blood contains immunologically naïve, hematopoietic stem cells known as HSCs which have been used in medical treatments for 25 years. They are capable of generating the multitude of cell types found in the bloodstream, including red blood cells or erythrocytes; different types of white blood cells, such as lymphocytes and neutrophils; and megakaryocytes which ultimately form platelets.
Track: Lung Cancer Stem Cells
Lung cancer remains a major cause of cancer-related lethality because of high incidence and recurrence in spite of significant advances in staging and therapies. Recent data indicates that stem cells situated throughout the airways may initiate cancer formation. These putative stem cells maintain protumorigenic characteristics including high proliferative capacity, multipotent differentiation, drug resistance and long lifespan relative to other cells. Stem cell signalling and differentiation pathways are maintained within distinct cancer types, and destabilization of this machinery may participate in maintenance of cancer stem cells. Characterization of lung cancer stem cells is an area of active research and is critical for developing novel therapies. This review summarizes the current knowledge on stem cell signalling pathways and cell markers used to identify the lung cancer stem cells.
Track: Prostate Cancer Stem Cells
Prostate Cancer is now a common disease in men over 50 years of age. Medical therapies for prostate cancer are based on discoveries from the mid-twentieth century, and in the long term are rarely curative. Most treatments are directed towards an androgen receptor-expressing, highly proliferative target cell, which does indeed form the vast majority of cells in a prostate tumour. However, by invoking the existence of a cancer stem cell which, like normal epithelial stem cells in the prostate, does not express androgen receptor and is relatively quiescent, the observed resistance to most medical therapies can be explained. The phenotype of the prostate cancer stem cells is that of a basal cell and cultures derived from cancers, but not benign tissues, express a range of prostate cancer-associated RNAs.
Track: Cancer Stem Cells in Solid Tumors
Cancer stem cells (CSCs) are cells that drive tumorigenesis, as well as giving rise to a large population of differentiated progeny that make up the bulk of the tumour, but that lack tumorigenic potential.
Track: Gynaecology oncology
Cervical Cancer is one of the most common cancers in women worldwide. But in the United States and other countries where cervical cancer screening is routine, this cancer is not so common. Most cervical cancer is caused by a virus called Human papillomavirus or also spelled as HPV. There are many types of the HPV virus, but all of HPV does not cause cervical cancer. Some of them cause genital warts, but other types may not show any Cervical Cancer symptoms and signs. An infection may go away on its own. But sometimes it can cause genital warts or can also lead to cervical cancer, it's important for women to have regular Pap tests. A Pap test can find changes in cervical cells before they turn into cancer cells. Thus treatment of these cell changes, prevent cervical cancer.
Track: Pediatric oncology
Pediatic Oncology is a branch of medicine which deals with the medical care of infants, children, and adolescents. The word pediatrics and its cognates mean "healer of children"; they derive from two Greek words: pais "child" and iatros "doctor, healer". The age limit, from birth up to 18-21 yrs. Pediatricians work both in primary care physicians and hospitals, especially they works in a specialized subfields such as neonatology. Paediatric oncologists diagnose, treat, and manage children, suffering from cancers which include leukaemia, lymphomas, brain tumours, bone tumours, and solid tumors. A medical practitioner who specializes in this area is called as a paediatrician. The body of an infant or neonate is substantially physiologically different when compare to an adult. Congenital defects, genetic variance and developmental issues are some greater concern to paediatricians as compare to adult physicians.
Track: Neuro Oncology
is the study of brain and spinal cord neoplasms, which are very
dangerous and leads to risking of life. Some of them are astrocytoma a
type of brain cancer; glioma is type of tumor starts at brain or spine, glioblastoma which is also called as glioblastoma multiforme (GBM), ependymoma, pontine glioma, and brain stem tumors. Brain tumors
can occur at any age of an individual, from primary stage to late in
life. Most of the primary tumours are found common in women. A person
who is trained in the diagnosis and treatment of nervous system is known
as Neuro oncologist. Primary malignant brain tumours are found 5,000
people in UK each year and others are found with secondary tumours.
Track: Carcinogenesis and Mutagenesis
Carcinogenesis also called as oncogenesis or tumorigenesis, leads to formation of a cancer, where normal cells are turned into cancerous. Thus the process is characterized by changes at epigenetic, genetic and cellular levels. The main idea of carcinogenesis is to check new group of oncogenes or tumour suppressor genes that may give new areas of research into cancer diagnosis, predicting clinical outcome of cancers and new targets for cancer therapies. There are also many epigenetic changes that alter whether genes are expressed or not expressed. The presence of an abnormal number of chromosomes in a gene is known as Aneuploidy. It is a genomic change, not a mutation. Large-scale mutations involve the deletion or gain of a portion of a chromosome. Genomic amplification occurs only when cell gains 20 or more than 20 copies of a small chromosomal region, containing one or more oncogenes and apart to it adjacent genetic material. Mutagenesis is a process by which, genetic information of an species or an organism is changed and thus results in a mutation and can lead to cancer and various heritable diseases, done by physical, chemical or biological agents. In the laboratories, Mutagenesis plays an important technique where, DNA mutations are intentionally engineered so that they can produce mutant strains, proteins, or Gene of an organism.
Track: Radiation Oncology
The use of radiation to treat cancer is defined as Radiation Oncology.
X-rays, gamma rays, or electrons are some of the radiations used to
treat the Radiation Oncology. A physician who uses ionizing radiation
(such as megavoltage X-rays or radionuclides) in the treatment of cancer
is known as Radiation Oncologist.
Thus Oncologists uses radiation to treat some of the benign diseases
and benign tumours. Radiation oncology is one of the primary specialties
among surgical and medical oncology,
which are involved in the treatment of cancer. The field of radiation
oncology gives the integration of radiation therapy into multimodal
treatment approaches. Radiation Oncology focuses on all aspects of
research, which impacts on the treatment of cancer using radiation. It
not only shows findings in molecular and cellular radiation biology but
also in wide range of radiation physics, radiation technology, and clinical oncology.
Track: Hemato-oncology and Blood Cancers
Hematologic oncology is the branch of medicine which deals with the study, diagnosis, treatment, and prevention of many diseases related to blood. Haematology involves the study of etiology. It involves the treatment of diseases which usually affect the production of blood and its components; it includes blood cells (RBC, WBC, etc…), haemoglobin, blood proteins, bone marrow, spleen, and also mechanism of coagulation. These kinds of diseases include hemophilia, blood clots, other bleeding disorders and mostly blood cancers such as leukaemia, myeloma, and lymphoma. Blood cancers affect the production of most of the blood cells in the body. These types of cancers start in patient’s bone marrow where the blood is produced. Stem cells mature and develop into three types of blood cells, which are White blood cells, red blood cells or platelets; they are smallest type of blood cell present in the bone marrow. The normal growth of blood cell is stopped by the uncontrolled growth of abnormal blood cells, which are generally cancerous.
Melanoma is one type of skin Cancer that arises when the melanocytes become cancerous. It is most common type of skin cancer but very serious if avoided. Melanoma, also called malignant melanoma, develops from the pigment-containing cells known as melanocytes. It typically occurs in the skin and rarely in the mouth, intestines, or eye. Individuals with low levels of skin pigment when expose to ultra violet light causes Melanoma. The use of sunscreen and avoiding UV light may prevent melanoma disease to a larger extent. Further treatment removal by surgery. Skin cancers are majorly arises from the skin. They are mainly due to abnormal growth of the cells that have the ability to spread to all other parts of the body of an individual. Basal-cell skin cancer (BCC), squamous-cell skin cancer (SCC) and melanoma are the common types of skin cancer seen in most of the individuals. Among these three BCC and SCC are commonly known as non-melanoma skin cancer (NMSC). Thus the non-melanoma skin cancer can be easily cured.