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Dr Lagadec is an assistant professor at the French National Institute of Health and Medical Research. He received his PhD in 2007 on TrkA signaling in breast cancer and spent 5 years as a postdoc fellowship in Dr. Pajonk’s lab, a pioneer in CSC research field. Within his time at UCLA in the Radiation Oncology Department at David Geffen School of Medicine, he got trained on CSC and was the first to demonstrated the phenotype plasticity of CSC induced by radiation treatment. Since 2012, Dr. lagadec set up is own team in the INSERM U908 laboratory in Lille, France, where he studies the molecular mechanisms involved in the reprogramming process. He develops molecular tools and an animal model to track and characterise CSC and iCSC. His domain of interest enlarges recently to understand the potential role of reprogramming in tumor dormancy and metastasis development.