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After graduating from the Royal College of Surgeons in Ireland in 2004 with a PhD in Oncology, Stephen Maher spent 3 years as a visiting fellow at the National Cancer Institute in the US. In 2007 he returned to Ireland and Trinity College Dublin, St. James’s Hospital as a research fellow. In 2010 he established his own research group having secured an Irish Cancer Society Fellowship and a number of Health Research Board grants, predominantly in the area of radiation resistance in the treatment of gastrointestinal malignancy. In 2012 Stephen moved to the University of Hull and Hull York Medical School as a senior lecturer, where he led the Cancer Biology and Therapeutics lab. In 2016 Stephen returned to Trinity College Dublin as the James Ussher Assistant Professor in Translational Oncology, where he has set up new cancer radiobiology and hypoxia research cores.
At the Department of Surgery, based at TCD and St. James’s Hospital Dublin, Stephen is primarily interested in understanding the complex molecular mechanisms underpinning resistance to radiotherapy and chemotherapy in oesophageal adenocarcinoma and malignant pleural mesothelioma. He is currently examining the role of microRNAs and cancer stems cells in driving resistance to treatment, and researching microRNA replacement therapy as a novel therapeutic to augment patient responses to conventional cytotoxics.