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Dr Ilio Vitale received his Ph.D. in 2006 for the molecular characterization of mitotic catastrophe. During his 6-years post-doc in France he investigated the role of aneuploidy/tetraploidy in tumorigenesis uncovering surveillance mechanisms surveying cell ploidy (EMBOJ 2010, Science 2012). He is currently Group Leader and Adjunct Professor in Neuobiology at the University of Rome “Tor Vergata” working on the link between CSCs, chromosomal instability, and tumor immunity. His group recently identified a novel strategy for the depletion of CSCs based on CHK1 inhibition (Gut 2017, Mol Cell 2017). He is the Executive Editor of Molecular & Cellular Oncology, Subject Editor in the Reference Module in Life Sciences and served as Editor for several books. He received the Young Scientist Award from the European Environmental Mutagenesis Society (2013). He is author of >100 ISI papers (including Science, Nat Med, Nat Rev Mol Cell Biol., Nat Cell Biol). “h” index: 34.
role of genomic and chromosome instability in oncogenesis. In particular, we are investigating the molecular mechanisms for maintaining genomic stability in CSCs and also evaluating the immunogenic potential of CSCs, with the major aim of developing novel strategies for efficient tumor eradication.